Capecitabine 500 mg film-coated tablets, 120 tablets — generic (India) Capecard (capecitabine) is a targeted cancer therapy. Delivery from Europe within 4-5 days, storage conditions are met, payment upon receipt. Order by calling +380996042415 on Viber.

Interchangeable drugs with the same active ingredient:

Capecard

Apsibin

Capetero

Capecibex 150

Capecibex 500

Capecitabine

Caponco

Xeloda

Newcapibine

Citine

Ental-Zdorovye

Indications:

Breast cancer:

• locally advanced or metastatic breast cancer, in combination with docetaxel after ineffective chemotherapy including anthracycline drugs;
• locally advanced or metastatic breast cancer, as monotherapy when ineffective Chemotherapy, including taxanes and anthracycline drugs, or if there is a contraindication to anthracycline therapy.

Colon cancer, colorectal cancer:

• Colon cancer, in adjuvant therapy after surgery for stage III cancer (Dukes stage C).
• Metastatic colorectal cancer.

Stomach cancer:

A drug for the first-line treatment of advanced gastric cancer, in combination with platinum-based drugs.

Contraindications .  History of severe, including unexpected reactions to treatment with fluoropyrimidines.  Hypersensitivity to capecitabine or to any component of the drug, or to fluorouracil.  Known deficiency of dihydropyrimidine dehydrogenase.  Pregnancy and breast-feeding.  Severe leukopenia, neutropenia, thrombocytopenia. Severe liver dysfunction.Severe renal failure (creatinine clearance Concomitant administration of sorivudine or its structural analogs such as brivudine.Contraindications to the use of any drug used in combination.

Method of administration and dosage.

Xeloda® can Prescribe only by a qualified physician experienced in the use of antineoplastic medicinal products. Careful monitoring during the first cycle of treatment is recommended for all patients.

Treatment should be discontinued if disease progression or unacceptable toxicity develops.

The drug is taken orally, no later than 30 minutes after meals, with water.

monotherapy

Colon, colorectal and breast cancerThe recommended daily dose of Xeloda®as adjuvant therapy is 2500 mg / m2body surface and is used in three-week cycles: take daily for 2 weeks, then take a week-long break. The total daily dose of Xeloda®divide into two doses (1250 mg / m 2body surface area in the morning and evening). The recommended total duration of adjuvant therapy in patients with stage III colon cancer is 6 months.

Combination therapy

Breast cancerin combination with docetaxel, the recommended dose for the treatment of metastatic cancer 22 times a day for 2 weeks followed by a break (in combination with docetaxel 75 mg / m2Once every 3 weeks as an infusion).Premedication with oral corticosteroids, such as dexamethasone, is performed before docetaxel administration in accordance with the docetaxel package insert for patients receiving a combination of capecitabine and docetaxel.

Colon cancer, colorectal cancer, stomach cancer:in the combination treatment regimen, the initial dose of Xeloda® must be reduced to 800-1000 mg/m22 times daily for 2 weeks followed by a week-long break or up to 625 mg / m 2 2 times a day with continuous use.When combined with irinotecan (200 mg / m 2 on day 1), the recommended dose is 800 mg / m 2 .2 .2 times daily for 2 weeks followed by a week-long break. The inclusion of bevacizumab in the combination regimen does not affect the starting dose of Xeloda.® .

Anti-emetic agents and premedication to ensure adequate hydration are prescribed to patients receiving Xeloda®®in combination with cisplatin or oxaliplatin before the administration of cisplatin in accordance with the instructions for use of cisplatin and oxaliplatin.General recommended The duration of adjuvant therapy in patients with stage III colon cancer is 6 months.

Xeloda Dose® are calculated based on body surface area. Tables 1 and 2 provide standard and reduced dose calculations (see "Dose Adjustments During Treatment") for the starting dose of Xeloda.® 1250 mg / m2 or 1000 mg/m2.